Our Mission

While cancer genomics have transformed our understanding of tumor pathophysiology and maintenance, cancer is not purely a genetic disease, but rather a disease of dysregulated cellular functions that result from aberrant protein interaction networks. The concept of this CRC/TRR is based on the view that the “language” by which proteins communicate is deregulated in cancer, thereby positioning post-translational modifications (PTMs) at the center of cancer development, maintenance and as a therapeutic avenue.